ENZYME entry: EC 1.14.11.8

Accepted Name
Trimethyllysine dioxygenase.
Alternative Name(s)
Epsilon-trimethyllysine 2-oxoglutarate dioxygenase.
TML dioxygenase.
TML hydroxylase.
TML-alpha-ketoglutarate dioxygenase.
TMLD.
Trimethyllysine alpha-ketoglutarate dioxygenase.
Trimethyllysine,2-oxoglutarate dioxygenase.
Reaction catalysed
N(6),N(6),N(6)-trimethyl-L-lysine + 2-oxoglutarate + O(2) <=> 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + succinate + CO(2)
Cofactor(s)
Fe(2+); L-ascorbate.
Cross-references
BRENDA1.14.11.8
EC2PDB1.14.11.8
ExplorEnz1.14.11.8
PRIAM enzyme-specific profiles1.14.11.8
KEGG Ligand Database for Enzyme Nomenclature1.14.11.8
IUBMB Enzyme Nomenclature1.14.11.8
IntEnz1.14.11.8
MEDLINEFind literature relating to 1.14.11.8
MetaCyc1.14.11.8
UniProtKB/Swiss-Prot
Q0VC74, TMLH_BOVIN;  Q5F4B3, TMLH_CHICK;  Q9NVH6, TMLH_HUMAN;  
Q91ZE0, TMLH_MOUSE;  Q96UB1, TMLH_NEUCR;  A5DCB6, TMLH_PICGU;  
Q91ZW6, TMLH_RAT;  

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