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ENZYME

ENZYME entry: EC 1.14.11.82

Accepted Name
5-dehydro-6-demethoxyfumagillol dioxygenase
Alternative Name(s)
Fma-C6H
Reaction catalysed
2-oxoglutarate + 5-dehydro-6-demethoxyfumagillol + O2 <=> 5-dehydro-6-demethoxy-6-hydroxyfumagillol + CO2 + succinate
Comment(s)
  • Requires iron(II).
  • The enzyme, characterized from the mold Aspergillus fumigatus, participates in the biosynthesis of the meroterpenoid fumagillin.
Cross-references
BRENDA1.14.11.82
EC2PDB1.14.11.82
ExplorEnz1.14.11.82
PRIAM enzyme-specific profiles1.14.11.82
KEGG Ligand Database for Enzyme Nomenclature1.14.11.82
IUBMB Enzyme Nomenclature1.14.11.82
IntEnz1.14.11.82
MEDLINEFind literature relating to 1.14.11.82
MetaCyc1.14.11.82
Rhea expert-curated reactions1.14.11.82
UniProtKB/Swiss-Prot
Q4WAZ3, FMAF_ASPFU

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