ENZYME entry: EC 1.14.12.13
| Accepted Name |
|---|
| 2-halobenzoate 1,2-dioxygenase.
|
| Alternative Name(s) |
|---|
| 2-chlorobenzoate 1,2-dioxygenase. |
| Reaction catalysed |
|---|
| A 2-halobenzoate + NADH + O(2) <=> catechol + a halide anion + NAD(+) + CO(2) |
| Cofactor(s) |
|---|
| Iron.
|
| Comment(s) |
|---|
- A multicomponent enzyme system composed of a dioxygenase component
and an electron transfer component.
- The latter contains FAD.
- The enzyme, characterized from the bacterium Burkholderia cepacia
2CBS, has a broad substrate specificity.
- Substrates include 2-fluorobenzoate, 2-chlorobenzoate,
2-bromobenzoate, and 2-iodobenzoate, which are processed in this
order of preference.
|
| Cross-references |
|---|
| BRENDA | 1.14.12.13 |
| EC2PDB | 1.14.12.13 |
| ExplorEnz | 1.14.12.13 |
| PRIAM enzyme-specific profiles | 1.14.12.13 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.12.13 |
| IUBMB Enzyme Nomenclature | 1.14.12.13 |
| IntEnz | 1.14.12.13 |
| MEDLINE | Find literature relating to 1.14.12.13 |
| MetaCyc | 1.14.12.13 |
| UniProtKB/Swiss-Prot |
|
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