ID   1.14.13.105
DE   monocyclic monoterpene ketone monooxygenase.
AN   1-hydroxy-2-oxolimonene 1,2-monooxygenase.
AN   dihydrocarvone 1,2-monooxygenase.
AN   MMKMO.
CA   (1) (1R,4S)-menthone + H(+) + NADPH + O2 = (4R,7S)-7-isopropyl-4-
CA   methyloxepan-2-one + H2O + NADP(+).
CA   (2) dihydrocarvone + H(+) + NADPH + O2 = 4-isopropenyl-7-methyloxepan-2-
CA   one + H2O + NADP(+).
CA   (3) dihydrocarvone + H(+) + NADPH + O2 = 6-isopropenyl-3-methyloxepan-2-
CA   one + H2O + NADP(+).
CA   (4) 1-hydroxylimonen-2-one + NADPH + O2 = 3-isopropenyl-6-oxoheptanoate +
CA   H2O + NADP(+).
CC   -!- This Baeyer-Villiger monooxygenase enzyme from the Gram-positive
CC       bacterium Rhodococcus erythropolis DCL14 has wide substrate
CC       specificity, catalyzing the lactonization of a large number of
CC       monocyclic monoterpene ketones and substituted cyclohexanones.
CC   -!- Both (1R,4S)- and (1S,4R)-1-hydroxymenth-8-en-2-one are metabolized,
CC       with the lactone product spontaneously rearranging to form
CC       3-isopropenyl-6-oxoheptanoate.
DR   P82679, MMKMO_RHOER;
//