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ENZYME entry: EC 1.14.13.123

Accepted Name
Germacrene A hydroxylase.
Reaction catalysed
(+)-germacrene A + NADPH + O(2) <=> germacra-1(10),4,11(13)-trien-12-ol + NADP(+) + H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • This is probably part of the biosynthesis of many sesquiterpenoid lactones.
  • In Lactuca sativa EC 1.14.13.213 is a mutifunctional enzyme with EC 1.1.1.314.
Cross-references
BRENDA1.14.13.123
EC2PDB1.14.13.123
ExplorEnz1.14.13.123
PRIAM enzyme-specific profiles1.14.13.123
KEGG Ligand Database for Enzyme Nomenclature1.14.13.123
IUBMB Enzyme Nomenclature1.14.13.123
IntEnz1.14.13.123
MEDLINEFind literature relating to 1.14.13.123
MetaCyc1.14.13.123
UniProtKB/Swiss-Prot
D5JBX1, GAO_BARSP;  D5JBW8, GAO_CICIN;  D5JBX0, GAO_HELAN;  
D5J9U8, GAO_LACSA;  D5JBW9, GAO_SAUCO;  

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