ENZYME entry: EC 1.14.13.132
| Accepted Name |
|---|
| Squalene monooxygenase.
|
| Alternative Name(s) |
|---|
| Squalene epoxidase. |
| Reaction catalysed |
|---|
| Squalene + NADPH + O(2) <=> (3S)-2,3-epoxy-2,3-dihydrosqualene + NADP(+) + H(2)O |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
- This enzyme, together with EC 5.4.99.7, was formerly known as
squalene oxidocyclase.
- The electron donor, NADPH, is coupled via EC 1.6.2.4.
- Formerly EC 1.14.1.3, EC 1.14.99.7 and EC 1.99.1.13.
|
| Cross-references |
|---|
| BRENDA | 1.14.13.132 |
| EC2PDB | 1.14.13.132 |
| ExplorEnz | 1.14.13.132 |
| PRIAM enzyme-specific profiles | 1.14.13.132 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.13.132 |
| IUBMB Enzyme Nomenclature | 1.14.13.132 |
| IntEnz | 1.14.13.132 |
| MEDLINE | Find literature relating to 1.14.13.132 |
| MetaCyc | 1.14.13.132 |
| UniProtKB/Swiss-Prot |
| O65404, ERG11_ARATH; | O65727, ERG11_BRANA; | O65402, ERG12_ARATH; |
| O65726, ERG12_BRANA; | O65403, ERG13_ARATH; | Q75F69, ERG1_ASHGO; |
| Q92206, ERG1_CANAL; | O13306, ERG1_CANGA; | Q14534, ERG1_HUMAN; |
| P52019, ERG1_MOUSE; | O48651, ERG1_PANGI; | P52020, ERG1_RAT; |
| Q9C1W3, ERG1_SCHPO; | P32476, ERG1_YEAST; |
|
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