ENZYME entry: EC 1.14.13.134

Accepted Name
Beta-amyrin 11-oxidase.
Alternative Name(s)
CYP88D6.
Reaction catalysed
Beta-amyrin + 2 O(2) + 2 NADPH <=> 11-oxo-beta-amyrin + 3 H(2)O + 2 NADP(+)
Comment(s)
  • Requires cytochrome P450.
  • Part of the glycyrrhizin biosynthesis pathway.
  • The enzyme is also able to oxidize 30-hydroxy-beta-amyrin to 11-alpha,30-dihydroxy-beta-amyrin but this is not thought to be part of glycyrrhizin biosynthesis.
Cross-references
BRENDA1.14.13.134
EC2PDB1.14.13.134
ExplorEnz1.14.13.134
PRIAM enzyme-specific profiles1.14.13.134
KEGG Ligand Database for Enzyme Nomenclature1.14.13.134
IUBMB Enzyme Nomenclature1.14.13.134
IntEnz1.14.13.134
MEDLINEFind literature relating to 1.14.13.134
MetaCyc1.14.13.134
UniProtKB/Swiss-Prot
B5BSX1, BAMO_GLYUR

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