ID   1.14.13.15
DE   Cholestanetriol 26-monooxygenase.
AN   5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase.
AN   5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol hydroxylase.
AN   Cholestanetriol 26-hydroxylase.
AN   Cholesterol 27-hydroxylase.
AN   Cytochrome P450 27A1'.
AN   Sterol 26-hydroxylase.
AN   Sterol 27-hydroxylase.
AN   Vitamin D(3) 25-hydroxylase.
CA   5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O(2) = (25R)-
CA   5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP(+) + H(2)O.
CF   Heme-thiolate.
CC   -!- Requires ferrodoxin.
CC   -!- Acts on cholesterol, cholest-5-en-3-beta,7-alpha-diol, 7-alpha-
CC       hydroxycholest-4-en-3-one, 5-beta-cholestane-3-alpha,7-alpha-diol as
CC       well as 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol.
CC   -!- With cholesterol as well as 26-hydroxycholesterol, 24-hydroxy- and
CC       25-hydroxycholesterol are also formed.
CC   -!- With prolonged treatment, 26-hydroxycholesterol is converted into the
CC       corresponding 27-aldehyde and 27-oic acid.
DR   Q02318, CP27A_HUMAN;  Q9DBG1, CP27A_MOUSE;  P17177, CP27A_RABIT;
DR   P17178, CP27A_RAT  ;  O46658, CP2DP_PIG  ;  Q6VVX0, CP2R1_HUMAN;
DR   Q6VVW9, CP2R1_MOUSE;  C4B644, CPVDH_PSEAH;
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