ID   1.14.13.154
DE   erythromycin 12 hydroxylase.
CA   erythromycin D + H(+) + NADPH + O2 = erythromycin C + H2O + NADP(+).
CC   -!- The enzyme is responsible for the C-12 hydroxylation of the
CC       macrolactone ring, one of the last steps in erythromycin
CC       biosynthesis.
CC   -!- It shows 1200-1900-fold preference for erythromycin D over the
CC       alternative substrate erythromycin B.
DR   P48635, ERYK_SACEN ;
//