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ENZYME entry: EC 1.14.13.173

Accepted Name
11-oxo-beta-amyrin 30-oxidase.
Alternative Name(s)
CYP72A.
CYP72A154.
Reaction catalysed
11-oxo-beta-amyrin + 3 O(2) + 3 NADPH <=> glycyrrhetinate + 3 NADP(+) + 4 H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • The enzyme is involved in the biosynthesis of the triterpenoid saponin glycyrrhizin in the plant Glycyrrhiza uralensis (licorice).
  • The enzyme from the plant Medicago truncatula can also hydroxylate beta-amyrin.
Cross-references
BRENDA1.14.13.173
EC2PDB1.14.13.173
ExplorEnz1.14.13.173
PRIAM enzyme-specific profiles1.14.13.173
KEGG Ligand Database for Enzyme Nomenclature1.14.13.173
IUBMB Enzyme Nomenclature1.14.13.173
IntEnz1.14.13.173
MEDLINEFind literature relating to 1.14.13.173
MetaCyc1.14.13.173
UniProtKB/Swiss-Prot
H1A988, C7254_GLYUR;  H1A981, C7263_MEDTR;  

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