ENZYME entry: EC 1.14.13.18

Accepted Name
4-hydroxyphenylacetate 1-monooxygenase.
Alternative Name(s)
4-HPA 1-hydroxylase.
4-hydroxyphenylacetate 1-hydroxylase.
4-hydroxyphenylacetic 1-hydroxylase.
Reaction catalysed
4-hydroxyphenylacetate + NAD(P)H + O(2) <=> homogentisate + NAD(P)(+) + H(2)O
Cofactor(s)
FAD.
Comment(s)
Also acts on 4-hydroxyhydratropate forming 2-methylhomogentisate and on 4-hydroxyphenoxyacetate forming hydroquinone and glycolate.
Cross-references
BRENDA1.14.13.18
EC2PDB1.14.13.18
ExplorEnz1.14.13.18
PRIAM enzyme-specific profiles1.14.13.18
KEGG Ligand Database for Enzyme Nomenclature1.14.13.18
IUBMB Enzyme Nomenclature1.14.13.18
IntEnz1.14.13.18
MEDLINEFind literature relating to 1.14.13.18
MetaCyc1.14.13.18

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