ENZYME entry: EC 1.14.13.180

Accepted Name
Aklavinone 12-hydroxylase.
Alternative Name(s)
Aklavinone 11-hydroxylase.
Reaction catalysed
Aklavinone + NADPH + O(2) <=> epsilon-rhodomycinone + NADP(+) + H(2)O
Cofactor(s)
FAD.
Comment(s)
The enzymes from the Gram-positive bacteria Streptomyces peucetius and Streptomyces purpurascens participate in the biosynthesis of daunorubicin, doxorubicin and rhodomycins.
Cross-references
BRENDA1.14.13.180
EC2PDB1.14.13.180
ExplorEnz1.14.13.180
PRIAM enzyme-specific profiles1.14.13.180
KEGG Ligand Database for Enzyme Nomenclature1.14.13.180
IUBMB Enzyme Nomenclature1.14.13.180
IntEnz1.14.13.180
MEDLINEFind literature relating to 1.14.13.180
MetaCyc1.14.13.180
UniProtKB/Swiss-Prot
P72495, DNRF_STRC0;  Q54530, DNRF_STREF;  P32009, DNRF_STRPE;  

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