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ENZYME entry: EC 1.14.13.182

Accepted Name
2-heptyl-3-hydroxy-4(1H)-quinolone synthase.
Alternative Name(s)
2-heptyl-3,4-dihydroxyquinoline synthase.
Reaction catalysed
2-heptyl-4(1H)-quinolone + NADH + O(2) <=> 2-heptyl-3-hydroxy-4(1H)-quinolone + NAD(+) + H(2)O
Comment(s)
The enzyme from the bacterium Pseudomonas aeruginosa catalyzes the terminal step in biosynthesis of the signal molecule 2-heptyl-3,4- dihydroxyquinoline that plays a role in regulation of virulence genes.
Cross-references
BRENDA1.14.13.182
EC2PDB1.14.13.182
ExplorEnz1.14.13.182
PRIAM enzyme-specific profiles1.14.13.182
KEGG Ligand Database for Enzyme Nomenclature1.14.13.182
IUBMB Enzyme Nomenclature1.14.13.182
IntEnz1.14.13.182
MEDLINEFind literature relating to 1.14.13.182
MetaCyc1.14.13.182
UniProtKB/Swiss-Prot
Q02N79, PQSH_PSEAB;  Q9I0Q0, PQSH_PSEAE;  

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