ENZYME entry: EC 1.14.13.186

Accepted Name
20-oxo-5-O-mycaminosyltylactone 23-monooxygenase.
Reaction catalysed
20-oxo-5-O-beta-mycaminosyltylactone + NADPH + O(2) <=> 5-O-beta-mycaminosyltylonolide + NADP(+) + H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
Involved in the biosynthetic pathway of the macrolide antibiotic tylosin, which is produced by several species of Streptomyces bacteria.
Cross-references
BRENDA1.14.13.186
EC2PDB1.14.13.186
ExplorEnz1.14.13.186
PRIAM enzyme-specific profiles1.14.13.186
KEGG Ligand Database for Enzyme Nomenclature1.14.13.186
IUBMB Enzyme Nomenclature1.14.13.186
IntEnz1.14.13.186
MEDLINEFind literature relating to 1.14.13.186
MetaCyc1.14.13.186
UniProtKB/Swiss-Prot
Q9ZHQ1, TYLH1_STRFR

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