ID   1.14.13.25
DE   methane monooxygenase (soluble).
AN   methane hydroxylase.
CA   (1) H(+) + methane + NADH + O2 = H2O + methanol + NAD(+).
CA   (2) H(+) + methane + NADPH + O2 = H2O + methanol + NADP(+).
CC   -!- The enzyme is soluble, in contrast to the particulate enzyme,
CC       EC 1.14.18.3.
CC   -!- Broad specificity; many alkanes can be hydroxylated, and alkenes are
CC       converted into the corresponding epoxides; CO is oxidized to CO2,
CC       ammonia is oxidized to hydroxylamine, and some aromatic compounds and
CC       cyclic alkanes can also be hydroxylated, but more slowly.
DR   P22869, MEMA_METCA ;  P27353, MEMA_METTR ;  P18798, MEMB_METCA ;
DR   P27354, MEMB_METTR ;  P11987, MEMG_METCA ;  P27355, MEMG_METTR ;
DR   P22868, MMOC_METCA ;  Q53563, MMOC_METTR ;
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