ENZYME entry: EC 1.14.13.41

Accepted Name
Tyrosine N-monooxygenase.
Alternative Name(s)
CYP79A1.
Tyrosine N-hydroxylase.
Reaction catalysed
L-tyrosine + 2 O(2) + 2 NADPH <=> (Z)-(4-hydroxyphenylacetaldehyde oxime) + 2 NADP(+) + CO(2) + 3 H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • Involved in the biosynthesis of the cyanogenic glucoside dhurrin in sorghum, along with EC 1.14.13.68 and EC 2.4.1.85.
  • Some 2-(4-hydroxyphenyl)-1-nitroethane is formed as a side product.
Cross-references
PROSITEPDOC00081
BRENDA1.14.13.41
EC2PDB1.14.13.41
ExplorEnz1.14.13.41
PRIAM enzyme-specific profiles1.14.13.41
KEGG Ligand Database for Enzyme Nomenclature1.14.13.41
IUBMB Enzyme Nomenclature1.14.13.41
IntEnz1.14.13.41
MEDLINEFind literature relating to 1.14.13.41
MetaCyc1.14.13.41
UniProtKB/Swiss-Prot
Q43135, C79A1_SORBI

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