ID   1.14.13.50
DE   pentachlorophenol monooxygenase.
AN   PCB4MO.
AN   PCB 4-monooxygenase.
AN   PCP hydroxylase.
AN   pentachlorophenol 4-monooxygenase.
AN   pentachlorophenol dechlorinase.
AN   pentachlorophenol dehalogenase.
AN   pentachlorophenol hydroxylase.
CA   (1) H(+) + NADPH + O2 + pentachlorophenol = 2,3,5,6-tetrachloro-1,4-
CA   benzoquinone + chloride + H2O + NADP(+).
CA   (2) 2,3,5,6-tetrachlorophenol + NADPH + O2 = 2,3,5,6-
CA   tetrachlorohydroquinone + H2O + NADP(+).
CC   -!- The enzyme displaces a diverse range of substituents from the
CC       4-position of polyhalogenated phenols but requires that a halogen
CC       substituent be present at the 2-position.
CC   -!- If C-4 carries a halogen substituent, reaction 1 is catalyzed; if C-4
CC       is unsubstituted, reaction 2 is catalyzed.
DR   P42535, PCPB_SPHCR ;
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