ENZYME entry: EC 1.14.13.52

Accepted Name
Isoflavone 3'-hydroxylase.
Reaction catalysed
Formononetin + NADPH + O(2) <=> calycosin + NADP(+) + H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • Also acts on biochanin A and other isoflavones with a 4'-methoxy group.
  • Involved in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain.
Cross-references
PROSITEPDOC00081
BRENDA1.14.13.52
EC2PDB1.14.13.52
ExplorEnz1.14.13.52
PRIAM enzyme-specific profiles1.14.13.52
KEGG Ligand Database for Enzyme Nomenclature1.14.13.52
IUBMB Enzyme Nomenclature1.14.13.52
IntEnz1.14.13.52
MEDLINEFind literature relating to 1.14.13.52
MetaCyc1.14.13.52
UniProtKB/Swiss-Prot
Q6WNQ9, C81E9_MEDTR

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