ENZYME entry: EC 1.14.13.69

Accepted Name
Alkene monooxygenase.
Alternative Name(s)
Alkene epoxygenase.
Reaction catalysed
Propene + NADH + O(2) <=> 1,2-epoxypropane + NAD(+) + H(2)O
Cofactor(s)
Fe cation.
Comment(s)
  • The enzyme from Xanthobacter sp. strain Py2 is a multicomponent enzyme comprising: (1) an NADH reductase, which provides the reductant for O(2) activation. (2) a Rieske-type ferredoxin, which is an electron-transfer protein. (3) an oxygenase, which contains the catalytic center for alkene epoxidation. (4) a small protein of unknown function that is essential for activity.
  • The enzyme oxygenates C(2) to C(6) aliphatic alkenes.
  • With propene as substrate, the stereospecificity of the epoxypropane formed is 95% (R) and 5% (S).
Cross-references
BRENDA1.14.13.69
EC2PDB1.14.13.69
ExplorEnz1.14.13.69
PRIAM enzyme-specific profiles1.14.13.69
KEGG Ligand Database for Enzyme Nomenclature1.14.13.69
IUBMB Enzyme Nomenclature1.14.13.69
IntEnz1.14.13.69
MEDLINEFind literature relating to 1.14.13.69
MetaCyc1.14.13.69

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