ENZYME entry: EC 1.14.13.78

Accepted Name
Ent-kaurene oxidase.
Reaction catalysed
  • Ent-kaur-16-ene + NADPH + O(2) <=> ent-kaur-16-en-19-ol + NADP(+) + H(2)O
  • Ent-kaur-16-en-19-ol + NADPH + O(2) <=> ent-kaur-16-en-19-al + NADP(+) + 2 H(2)O
  • Ent-kaur-16-en-19-al + NADPH + O(2) <=> ent-kaur-16-en-19-oate + NADP(+) + H(2)O
Comment(s)
  • Requires cytochrome P450.
  • Catalyzes three sucessive oxidations of the 4-methyl group of ent- kaurene giving kaurenoic acid.
Cross-references
PROSITEPDOC00081
BRENDA1.14.13.78
EC2PDB1.14.13.78
ExplorEnz1.14.13.78
PRIAM enzyme-specific profiles1.14.13.78
KEGG Ligand Database for Enzyme Nomenclature1.14.13.78
IUBMB Enzyme Nomenclature1.14.13.78
IntEnz1.14.13.78
MEDLINEFind literature relating to 1.14.13.78
MetaCyc1.14.13.78
UniProtKB/Swiss-Prot
Q5Z5R4, C7016_ORYSJ;  Q93ZB2, KO1_ARATH;  O94142, KO1_GIBFU;  
Q701P2, KO1_GIBIN;  

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