ENZYME entry: EC 1.14.13.92

Accepted Name
Phenylacetone monooxygenase.
Alternative Name(s)
PAMO.
Reaction catalysed
Phenylacetone + NADPH + O(2) <=> benzyl acetate + NADP(+) + H(2)O
Cofactor(s)
FAD.
Comment(s)
  • NADH cannot replace NADPH as coenzyme.
  • In addition to phenylacetone, which is the best substrate found to date, this Baeyer-Villiger monooxygenase can oxidize other aromatic ketones (1-(4-hydroxyphenyl)propan-2-one, 1-(4-hydroxyphenyl)propan- 2-one and 3-phenylbutan-2-one), some alipatic ketones (e.g. dodecan- 2-one) and sulfides (e.g. 1-methyl-4-(methylsulfanyl)benzene).
Cross-references
BRENDA1.14.13.92
EC2PDB1.14.13.92
ExplorEnz1.14.13.92
PRIAM enzyme-specific profiles1.14.13.92
KEGG Ligand Database for Enzyme Nomenclature1.14.13.92
IUBMB Enzyme Nomenclature1.14.13.92
IntEnz1.14.13.92
MEDLINEFind literature relating to 1.14.13.92
MetaCyc1.14.13.92
UniProtKB/Swiss-Prot
Q47PU3, PAMO_THEFY

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.13.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-