ID 1.14.14.106 DE taxane 13alpha-hydroxylase. AN CYP725A2. CA taxa-4(20),11-dien-5alpha-ol + reduced [NADPH--hemoprotein reductase] + CA O2 = taxa-4(20),11-dien-5alpha,13alpha-diol + oxidized [NADPH- CA -hemoprotein reductase] + H2O + H(+). CC -!- This cytochrome-P450(heme-thiolate) enzyme from the plant Taxus CC cuspidata is involved in the biosynthesis of the diterpenoid CC antineoplastic drug taxol (paclitaxel). CC -!- Formerly EC 1.14.13.77. DR Q8W4T9, T13H_TAXCU ; //