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ENZYME entry: EC

Accepted Name
4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase.
Reaction catalysed
4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] + FMNH(2) + O(2) <=> 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI acyl-carrier protein] + FMN + H(2)O
  • Catalyzes a step in the biosynthesis of the side chain of the aminoglycoside antibiotics of the butirosin family.
  • Forms a complex with a dedicated NAD(P)H:FMN oxidoreductase.
  • The enzyme is not able to hydroxylate free substrates, activation by the acyl-carrier protein is mandatory.
  • Octanoyl-S-[BtrI acyl-carrier protein] is also accepted.
PRIAM enzyme-specific profiles1.14.14.13
KEGG Ligand Database for Enzyme Nomenclature1.14.14.13
IUBMB Enzyme Nomenclature1.14.14.13
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
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