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ENZYME

ENZYME entry: EC 1.14.14.189

PURL: https://purl.expasy.org/enzyme/EC/1.14.14.189
Accepted Name
strychnine 10-hydroxylase
Alternative Name(s)
CYP82D36
Reaction catalysed
strychnine + reduced [NADPH--hemoprotein reductase] + O2 = 10-hydroxystrychnine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Comment(s)
  • A cytochrome P450 (heme-thiolate) protein.
  • The enzyme, isolated from the tree Strychnos nux-vomica, participates in the biosynthesis of brucine.
Cross-references
BRENDA1.14.14.189
EC2PDB1.14.14.189
ExplorEnz1.14.14.189
KEGG Ligand Database for Enzyme Nomenclature1.14.14.189
IUBMB Enzyme Nomenclature1.14.14.189
MEDLINEFind literature relating to 1.14.14.189
MetaCyc1.14.14.189
Rhea expert-curated reactions1.14.14.189
UniProtKB/Swiss-Prot
P0DO85, 10H_STRNX

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