Expasy logo

ENZYME

ENZYME entry: EC 1.14.14.49

Accepted Name
12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase
Alternative Name(s)
CYP94C1
Reaction catalysed
a 12-hydroxyjasmonyl-L-alpha-amino acid + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> a 12-hydroxy-12-oxojasmonyl-L-alpha-amino acid + 3 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]
Comment(s)
  • The enzyme, found in plants, acts on jasmonoyl-L-amino conjugates that have been hydroxylated at the C-12 position of the jasmonic acid chain by EC 1.14.14.48 further oxidizing that position to a carboxylate via an aldehyde intermediate.
  • While the best studied substrate is (+)-7-iso-jasmonoyl-L-isoleucine, the enzyme was shown to be active with jasmonoyl-L-phenylalanine, and is likely to be active with other jasmonoyl-amino acid conjugates.
Cross-references
BRENDA1.14.14.49
EC2PDB1.14.14.49
ExplorEnz1.14.14.49
PRIAM enzyme-specific profiles1.14.14.49
KEGG Ligand Database for Enzyme Nomenclature1.14.14.49
IUBMB Enzyme Nomenclature1.14.14.49
IntEnz1.14.14.49
MEDLINEFind literature relating to 1.14.14.49
MetaCyc1.14.14.49
Rhea expert-curated reactions1.14.14.49
UniProtKB/Swiss-Prot
Q9ZUX1, C94C1_ARATH

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-