ID   1.14.15.6
DE   Cholesterol monooxygenase (side-chain-cleaving).
AN   Cholesterol 20-22-desmolase.
AN   Cholesterol C(20-22) desmolase.
AN   Cholesterol desmolase.
AN   Cholesterol side-chain cleavage enzyme.
AN   Cholesterol side-chain-cleaving enzyme.
AN   Cytochrome P-450(scc).
AN   Cytochrome p450(scc).
AN   Steroid 20-22 desmolase.
AN   Steroid 20-22-lyase.
CA   Cholesterol + reduced adrenal ferredoxin + O(2) = pregnenolone +
CA   4-methylpentanal + oxidized adrenal ferredoxin + H(2)O.
CF   Heme-thiolate.
CC   -!- The reaction proceeds in three stages, with hydroxylation at C-20 and
CC       C-22 preceding scission of the side-chain at C-20.
PR   PROSITE; PDOC00081;
DR   P00189, CP11A_BOVIN;  P79153, CP11A_CAPHI;  Q92045, CP11A_DASAM;
DR   O46515, CP11A_HORSE;  P05108, CP11A_HUMAN;  Q2XV99, CP11A_MACFA;
DR   Q9EPT4, CP11A_MESAU;  Q9QZ82, CP11A_MOUSE;  Q07217, CP11A_ONCMY;
DR   P10612, CP11A_PIG  ;  Q28827, CP11A_RABIT;  P14137, CP11A_RAT  ;
DR   P79202, CP11A_SHEEP;
//