ENZYME entry: EC 1.14.18.1

Accepted Name
Monophenol monooxygenase.
Alternative Name(s)
Cresolase.
Monophenol oxidase.
Phenolase.
Tyrosinase.
Reaction catalysed
L-tyrosine + L-dopa + O(2) <=> L-dopa + dopaquinone + H(2)O
Cofactor(s)
Copper.
Comment(s)
  • A group of copper proteins that also catalyze the reaction of EC 1.10.3.1, if only 1,2-benzenediols are available as substrate.
  • Formerly EC 1.14.17.2.
Cross-references
PROSITEPDOC00398
BRENDA1.14.18.1
EC2PDB1.14.18.1
ExplorEnz1.14.18.1
PRIAM enzyme-specific profiles1.14.18.1
KEGG Ligand Database for Enzyme Nomenclature1.14.18.1
IUBMB Enzyme Nomenclature1.14.18.1
IntEnz1.14.18.1
MEDLINEFind literature relating to 1.14.18.1
MetaCyc1.14.18.1
UniProtKB/Swiss-Prot
Q00024, PPO1_AGABI;  O42713, PPO2_AGABI;  C7FF04, PPO3_AGABI;  
C7FF05, PPO4_AGABI;  Q27451, PRP1_BOMMO;  O44249, PRP1_MANSE;  
P85046, PRP1_SIMDA;  Q27452, PRP2_BOMMO;  Q25519, PRP2_MANSE;  
Q9V521, PRPA3_DROME;  Q8I1F6, PRPD3_DROER;  Q9W1V6, PRPD3_DROME;  
Q8J130, TYRO_ASPFU;  Q00234, TYRO_ASPOR;  Q8MIU0, TYRO_BOVIN;  
P54834, TYRO_CANFA;  P55024, TYRO_CHICK;  Q08410, TYRO_COTJA;  
P55033, TYRO_FELCA;  Q9BDE0, TYRO_GORGO;  P14679, TYRO_HUMAN;  
P11344, TYRO_MOUSE;  P00440, TYRO_NEUCR;  P55025, TYRO_ORYLA;  
Q04604, TYRO_PELNI;  P55026, TYRO_PELSI;  A7BHQ9, TYRO_PHONA;  
Q92396, TYRO_PODAS;  P33180, TYRO_RHIML;  P07524, TYRO_STRAT;  
P06845, TYRO_STRGA;  P55022, TYRO_STRGB;  P55023, TYRO_STRLN;  

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