ID   1.14.18.10
DE   plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase.
CA   24-methylenecycloartanol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 =
CA   4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-
CA   24(24(1))-en-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O.
CC   -!- This plant enzyme catalyzes a step in the biosynthesis of sterols.
CC   -!- It acts on the 4alpha-methyl group of the 4,4-dimethylated
CC       intermediate 24-methylenecycloartanol and catalyzes three successive
CC       oxidations, turning it into a carboxyl group.
CC   -!- The carboxylate is subsequently removed by EC 1.1.1.418, which also
CC       catalyzes the epimerization of the remaining 4beta-methyl into the
CC       4alpha position.
CC   -!- Unlike the fungal/animal enzyme EC 1.14.18.9, this enzyme is not able
CC       to remove the methyl group from C-4-monomethylated substrates.
CC   -!- That activity is performed in plants by a second enzyme,
CC       EC 1.14.18.11.
DR   Q8L7W5, SMO11_ARATH;  Q1EC69, SMO12_ARATH;
//