ID   1.14.18.7
DE   dihydroceramide fatty acyl 2-hydroxylase.
AN   plant sphingolipid fatty acid 2-hydroxylase.
CA   an N-(1,2-saturated acyl)sphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+)
CA   + O2 = an N-[(2'R)-hydroxyacyl]sphinganine + 2 Fe(III)-[cytochrome b5] +
CA   H2O.
CC   -!- The enzyme, characterized from plants, catalyzes the hydroxylation of
CC       carbon 2 of long- or very-long-chain fatty acids attached to
CC       sphinganine during de novo ceramide synthesis.
CC   -!- The enzyme requires an external cytochrome b5 as the electron donor.
CC   -!- The newly introduced 2-hydroxyl group has R-configuration. cf.
CC       EC 1.14.18.6.
DR   O48916, FAH1_ARATH ;  Q9SUC5, FAH2_ARATH ;  Q03529, SCS7_YEAST ;
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