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ENZYME

ENZYME entry: EC 1.14.19.1

Accepted Name
stearoyl-CoA 9-desaturase
Alternative Name(s)
acyl-CoA desaturase
Delta(9)-desaturase
fatty acid desaturase
stearoyl-CoA desaturase
Reaction catalysed
2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + octadecanoyl-CoA <=> (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
Comment(s)
  • The liver enzyme is an enzyme system involving cytochrome b5 and EC 1.6.2.2.
  • The ferricytochrome b5 produced is reduced by NADH and EC 1.6.2.2.
  • Formerly EC 1.14.99.5.
Cross-references
BRENDA1.14.19.1
EC2PDB1.14.19.1
ExplorEnz1.14.19.1
PRIAM enzyme-specific profiles1.14.19.1
KEGG Ligand Database for Enzyme Nomenclature1.14.19.1
IUBMB Enzyme Nomenclature1.14.19.1
IntEnz1.14.19.1
MEDLINEFind literature relating to 1.14.19.1
MetaCyc1.14.19.1
Rhea expert-curated reactions1.14.19.1
UniProtKB/Swiss-Prot
Q12618, ACO1_AJECAO94523, ACO1_SCHPOP21147, ACO1_YEAST
P13516, ACOD1_MOUSEP07308, ACOD1_RATQ92038, ACOD_CYPCA
O62849, ACOD_SHEEPQ9BH41, FAD9_ACHDOG5EGN2, FAT6_CAEEL
G5EGH6, FAT7_CAEELA0A0C5Q309, SCD1_TACFUP13011, SCD2_MOUSE
Q6P7B9, SCD2_RATQ6T707, SCD4_MOUSEQ2KIA4, SCD5_BOVIN
Q86SK9, SCD5_HUMANQ9TT94, SCD_BOVINQ95MI7, SCD_CAPHI
O00767, SCD_HUMANQ64420, SCD_MESAUO02858, SCD_PIG

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