ID   1.14.19.19
DE   sphingolipid 10-desaturase.
CA   a (4E,8E)-4-sphinga-4,8-dienine ceramide + 2 Fe(II)-[cytochrome b5] +
CA   O2 + 2 H(+) = an N-acyl-(4E,8E,10E)-sphingatrienine + 2 Fe(III)-
CA   [cytochrome b5] + 2 H2O.
CC   -!- The enzyme, characterized from the marine diatom Thalassiosira
CC       pseudonana, produces an all-trans product.
CC   -!- Similar triunsaturated sphingoid bases are found in some marine
CC       invertebrates.
CC   -!- The enzyme determines the position of the double bond by its distance
CC       from the alcohol end of the sphingoid base, and contains a cytochrome
CC       b5 domain that acts as the direct electron donor to the active site
CC       of the desaturase.
DR   Q4G2T3, DESAT_THAPS;
//