Expasy logo

ENZYME

ENZYME entry: EC 1.14.19.37

Accepted Name
acyl-CoA 5-desaturase
Alternative Name(s)
acyl-CoA 5-desaturase (non-methylene-interrupted)
Reaction catalysed
  • (11Z,14Z)-eicosadienoyl-CoA + AH2 + O2 <=> (5Z,11Z,14Z)-eicosatrienoyl-CoA + A + 2 H2O
  • (11Z,14Z,17Z)-eicosatrienoyl-CoA + AH2 + O2 <=> (5Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + A + 2 H2O
Comment(s)
  • The enzyme, characterized from the plant Anemone leveillei, introduces a cis double bond at carbon 5 of acyl-CoAs that do not contain a double bond at position 8.
  • In vivo it forms non-methylene-interrupted polyunsaturated fatty acids such as sciadonate and juniperonate.
  • When expressed in Arabidopsis thaliana the enzyme could also act on unsaturated substrates such as palmitoyl-CoA. cf. EC 1.14.19.44.
Cross-references
BRENDA1.14.19.37
EC2PDB1.14.19.37
ExplorEnz1.14.19.37
PRIAM enzyme-specific profiles1.14.19.37
KEGG Ligand Database for Enzyme Nomenclature1.14.19.37
IUBMB Enzyme Nomenclature1.14.19.37
IntEnz1.14.19.37
MEDLINEFind literature relating to 1.14.19.37
MetaCyc1.14.19.37
Rhea expert-curated reactions1.14.19.37
UniProtKB/Swiss-Prot
P0DOW2, AL10_ANELEP0DOW3, AL21_ANELEG5EG11, FAT4_CAEEL

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.19.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-