ID   1.14.19.37
DE   acyl-CoA 5-desaturase.
AN   acyl-CoA 5-desaturase (non-methylene-interrupted).
CA   (1) (11Z,14Z)-eicosadienoyl-CoA + AH2 + O2 = (5Z,11Z,14Z)-eicosatrienoyl-
CA   CoA + A + 2 H2O.
CA   (2) (11Z,14Z,17Z)-eicosatrienoyl-CoA + AH2 + O2 = (5Z,11Z,14Z,17Z)-
CA   eicosatetraenoyl-CoA + A + 2 H2O.
CC   -!- The enzyme, characterized from the plant Anemone leveillei,
CC       introduces a cis double bond at carbon 5 of acyl-CoAs that do not
CC       contain a double bond at position 8.
CC   -!- In vivo it forms non-methylene-interrupted polyunsaturated fatty
CC       acids such as sciadonate and juniperonate.
CC   -!- When expressed in Arabidopsis thaliana the enzyme could also act on
CC       unsaturated substrates such as palmitoyl-CoA. cf. EC 1.14.19.44.
DR   P0DOW2, AL10_ANELE ;  P0DOW3, AL21_ANELE ;  G5EG11, FAT4_CAEEL ;
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