ID   1.14.19.5
DE   Delta(11)-fatty-acid desaturase.
AN   Delta(11) desaturase.
AN   Delta(11)-palmitoyl-CoA desaturase.
AN   Fatty acid Delta(11)-desaturase.
AN   Z/E11-desaturase.
CA   Acyl-CoA + reduced acceptor + O(2) = Delta(11)-acyl-CoA + acceptor +
CA   2 H(2)O.
CC   -!- In common with front-end desaturases involved in the synthesis of
CC       polyunsaturated fatty acids (PUFAs), this membrane-bound enzyme has a
CC       cytochrome b5-like domain at the N-terminus and contains three
CC       histidine boxes that are critical for desaturase activity.
CC   -!- The enzyme from the marine microalga Thalassiosira pseudonana
CC       specifically desaturates palmitic acid 16:0 to 16:1-Delta(11) whereas
CC       that from the leafroller moth Choristoneura rosaceana desaturates
CC       myristic acid 14:0 to 14:1-Delta(11).
CC   -!- 16:1-Delta(11) represents an important precursor for pheromone
CC       synthesis in insect cells, although its function in microalgae is
CC       currently unknown.
CC   -!- The enzyme from the Egyptian cotton leafworm Spodoptera littoralis
CC       has a preference for palmitoyl-CoA as substrate and for NADH rather
CC       than NADPH as reduced acceptor.
CC   -!- Formerly EC 1.14.19.n2.
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