ID 1.14.19.66 DE berbamunine synthase. AN (S)-N-methylcoclaurine oxidase (C-O phenol-coupling). CA (R)-N-methylcoclaurine + (S)-N-methylcoclaurine + reduced [NADPH- CA -hemoprotein reductase] + O2 = berbamunine + oxidized [NADPH--hemoprotein CA reductase] + 2 H2O + H(+). CC -!- A cytochrome P450 (heme-thiolate) protein found in plants. CC -!- Forms the bisbenzylisoquinoline alkaloid berbamunine by phenol CC oxidation of N-methylcoclaurine without the incorporation of oxygen CC into the product. CC -!- Reaction of two molecules of (R)-N-methylcoclaurine gives the dimer CC guattagaumerine. CC -!- Formerly EC 1.1.3.34 and EC 1.14.21.3. DR P47195, C80A1_BERST; //