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ENZYME

ENZYME entry: EC 1.14.19.71

Accepted Name
fumitremorgin C synthase
Reaction catalysed
O2 + reduced [NADPH--hemoprotein reductase] + tryprostatin A <=> fumitremorgin C + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]
Comment(s)
  • A cytochrome P450 (heme-thiolate) protein.
  • The protein from the fungus Aspergillus fumigatus also has activity with tryprostatin B forming demethoxyfumitremorgin C.
  • Involved in the biosynthetic pathways of several indole alkaloids such as fumitremorgins and verruculogen.
  • Formerly EC 1.14.21.10.
Cross-references
BRENDA1.14.19.71
EC2PDB1.14.19.71
ExplorEnz1.14.19.71
PRIAM enzyme-specific profiles1.14.19.71
KEGG Ligand Database for Enzyme Nomenclature1.14.19.71
IUBMB Enzyme Nomenclature1.14.19.71
IntEnz1.14.19.71
MEDLINEFind literature relating to 1.14.19.71
MetaCyc1.14.19.71
Rhea expert-curated reactions1.14.19.71
UniProtKB/Swiss-Prot
B9WZX4, FTME_ASPFMQ4WAW8, FTME_ASPFUA1DA63, FTME_NEOFI

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