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ENZYME

ENZYME entry: EC 1.14.20.10

Accepted Name
tyrosine isonitrile desaturase/decarboxylase
Reaction catalysed
(2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 <=> 4-[(E)-2-isocyanoethenyl]phenol + 2 CO2 + H2O + succinate
Comment(s)
  • The enzyme, characterized from the bacterium Xenorhabdus nematophila, is involved in rhabduscin biosynthesis.
  • The enzyme is a member of the Fe(2+), 2-oxoglutarate-dependent oxygenases.
  • It is similar to EC 1.14.20.9; however, the latter does not catalyze a decarboxylation of the substrate.
Cross-references
BRENDA1.14.20.10
EC2PDB1.14.20.10
ExplorEnz1.14.20.10
PRIAM enzyme-specific profiles1.14.20.10
KEGG Ligand Database for Enzyme Nomenclature1.14.20.10
IUBMB Enzyme Nomenclature1.14.20.10
IntEnz1.14.20.10
MEDLINEFind literature relating to 1.14.20.10
MetaCyc1.14.20.10
Rhea expert-curated reactions1.14.20.10
UniProtKB/Swiss-Prot
D3V9Q5, PVCB_XENNA

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