Due to maintenance work, this service will not be available on Monday December 12th between 07.00 am and 9.00 am CEST.

ENZYME entry: EC 1.14.20.3

Accepted Name
(5R)-carbapenem-3-carboxylate synthase.
Reaction catalysed
(3S,5S)-carbapenam-3-carboxylate + 2-oxoglutarate + O(2) <=> (5R)-carbapen-2-em-3-carboxylate + succinate + CO(2) + H(2)O
Cofactor(s)
Fe(2+).
Comment(s)
  • The enzyme is involved in the biosynthesis of the carbapenem beta- lactam antibiotic (5R)-carbapen-2-em-3-carboxylate in the bacterium Pectobacterium carotovorum.
  • It catalyzes a stereoinversion at C(5) and introduces a double bond between C-2 and C-3.
Cross-references
BRENDA1.14.20.3
EC2PDB1.14.20.3
ExplorEnz1.14.20.3
PRIAM enzyme-specific profiles1.14.20.3
KEGG Ligand Database for Enzyme Nomenclature1.14.20.3
IUBMB Enzyme Nomenclature1.14.20.3
IntEnz1.14.20.3
MEDLINEFind literature relating to 1.14.20.3
MetaCyc1.14.20.3
UniProtKB/Swiss-Prot
Q9XB59, CARC_PECCC

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.20.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-