ID   1.14.20.8
DE   (-)-deoxypodophyllotoxin synthase.
CA   (-)-yatein + 2-oxoglutarate + O2 = (-)-deoxypodophyllotoxin + CO2 + H2O +
CA   succinate.
CC   -!- The enzyme, characterized from the plant Sinopodophyllum hexandrum,
CC       is involved in the biosynthetic pathway of podophyllotoxin, a non-
CC       alkaloid toxin lignan whose derivatives are important anticancer
CC       drugs.
CC   -!- It catalyzes the closure of the central six-membered ring in the
CC       aryltetralin scaffold.
CC   -!- Formerly EC 1.14.11.50.
DR   A0A0N9HQ36, 2ODD_SINHE ;
//