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ENZYME entry: EC 1.14.99.42

Accepted Name
Zeaxanthin 7,8-dioxygenase.
Alternative Name(s)
Zeaxanthin 7,8(7',8')-cleavage dioxygenase.
Reaction catalysed
Zeaxanthin + 2 O(2) <=> crocetin dialdehyde + 2 (3S)-3-hydroxycyclocitral
Comment(s)
  • The enzyme, characterized from the plant Crocus sativus, acts twice on zeaxanthin, cleaving 3-hydroxycyclocitral off each 3-hydroxy end group.
  • It is part of the zeaxanthin degradation pathway in that organism, leading to the different compounds that impart the color, flavor and aroma of the saffron spice.
  • Formerly EC 1.14.99.n3.
Cross-references
BRENDA1.14.99.42
EC2PDB1.14.99.42
ExplorEnz1.14.99.42
PRIAM enzyme-specific profiles1.14.99.42
KEGG Ligand Database for Enzyme Nomenclature1.14.99.42
IUBMB Enzyme Nomenclature1.14.99.42
IntEnz1.14.99.42
MEDLINEFind literature relating to 1.14.99.42
MetaCyc1.14.99.42
UniProtKB/Swiss-Prot
Q84K96, ZCD_CROSA

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