ENZYME entry: EC 1.14.99.53

Accepted Name
Lytic chitin monooxygenase.
Alternative Name(s)
Chitin oxidohydrolase.
LPMO.
Reaction catalysed
((1->4)-N-acetyl-beta-D-glucosaminyl)(n+m) + reduced acceptor + O(2) <=> ((1->4)-N-acetyl-beta-D-glucosaminyl)(m-1)-(1->4)-2-(acetylamino)-2-deoxy-D-glucono-1,5-lactone + ((1->4)-N-acetyl-beta-D-glucosaminyl)(n) + acceptor + H(2)O
Cofactor(s)
Cu(2+).
Comment(s)
  • The enzyme cleaves chitin in an oxidative manner, releasing fragments of chitin with an N-acetylamino-D-glucono-1,5-lactone at the reducing end.
  • The initially formed lactone at the reducing end of the shortend chitin chain quickly hydrolyzes spontaneously to the aldonic acid.
  • In vitro ascorbate can serve as reducing agent.
Cross-references
BRENDA1.14.99.53
EC2PDB1.14.99.53
ExplorEnz1.14.99.53
PRIAM enzyme-specific profiles1.14.99.53
KEGG Ligand Database for Enzyme Nomenclature1.14.99.53
IUBMB Enzyme Nomenclature1.14.99.53
IntEnz1.14.99.53
MEDLINEFind literature relating to 1.14.99.53
MetaCyc1.14.99.53

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-