ID 1.16.1.10 DE ferric-chelate reductase [NAD(P)H]. AN ferric reductase. CA (1) 2 a Fe(II)-siderophore + H(+) + NAD(+) = 2 a Fe(III)-siderophore + CA NADH. CA (2) 2 a Fe(II)-siderophore + H(+) + NADP(+) = 2 a Fe(III)-siderophore + CA NADPH. CC -!- The enzyme catalyzes the reduction of bound ferric iron in a variety CC of iron chelators (siderophores), resulting in the release of ferrous CC iron. CC -!- The enzyme from the hyperthermophilic archaeon Archaeoglobus fulgidus CC is not active with uncomplexed Fe(III). cf. EC 1.16.1.7 and CC EC 1.16.1.9. DR O29428, FERCR_ARCFU; A0A1W7HCY1, IUTB_VIBVL ; //