ID 1.16.1.8 DE [Methionine synthase] reductase. AN [Methionine synthase]-cobalamin methyltransferase (cob(II)alamin AN reducing). AN Methionine synthase cob(II)alamin reductase (methylating). AN Methionine synthase reductase. CA 2 [methionine synthase]-methylcob(I)alamin + 2 S-adenosylhomocysteine + CA NADP(+) = 2 [methionine synthase]-cob(II)alamin + NADPH + 2 S-adenosyl-L- CA methionine. CF FAD; FMN. CC -!- The substrate of the enzyme is the inactivated [Co(II)] form of CC EC 2.1.1.13. CC -!- Electrons are transferred from NADPH to FAD to FMN. CC -!- Formerly EC 2.1.1.135. DR Q4JIJ2, MTRR_BOVIN ; Q17574, MTRR_CAEEL ; Q9UBK8, MTRR_HUMAN ; DR Q8C1A3, MTRR_MOUSE ; Q498R1, MTRR_RAT ; //