ID 1.17.1.3 DE leucoanthocyanidin reductase. AN leucocyanidin reductase. CA (2R,3S)-catechin + H2O + NADP(+) = (2R,3S,4S)-leucocyanidin + H(+) + CA NADPH. CC -!- Catalyzes the synthesis of catechin, catechin-4beta-ol CC (leucocyanidin) and the related flavan-3-ols afzelechin and CC gallocatechin, which are initiating monomers in the synthesis of CC plant polymeric proanthocyanidins or condensed tannins. CC -!- While 2,3-trans-3,4-cis-leucocyanidin is the preferred flavan-3,4- CC diol substrate, 2,3-trans-3,4-cis-leucodelphinidin and 2,3-trans-3, CC 4-cis-leucopelargonidin can also act as substrates, but more slowly. CC -!- NADH can replace NADPH but is oxidized more slowly. DR Q84V83, LAR_DESUN ; //