ENZYME entry: EC 1.2.1.3

Accepted Name
Aldehyde dehydrogenase (NAD(+)).
Reaction catalysed
An aldehyde + NAD(+) + H(2)O <=> a carboxylate + NADH
Comment(s)
  • Wide specificity, including oxidation of D-glucuronolactone to D-glucarate.
  • Formerly EC 1.1.1.70.
Cross-references
PROSITEPDOC00068
BRENDA1.2.1.3
EC2PDB1.2.1.3
ExplorEnz1.2.1.3
PRIAM enzyme-specific profiles1.2.1.3
KEGG Ligand Database for Enzyme Nomenclature1.2.1.3
IUBMB Enzyme Nomenclature1.2.1.3
IntEnz1.2.1.3
MEDLINEFind literature relating to 1.2.1.3
MetaCyc1.2.1.3
UniProtKB/Swiss-Prot
Q7ZVB2, A9A1A_DANRE;  Q802W2, A9A1B_DANRE;  O35945, AL1A7_MOUSE;  
P13601, AL1A7_RAT;  P52476, AL1B1_BOVIN;  P30837, AL1B1_HUMAN;  
Q9CZS1, AL1B1_MOUSE;  Q5R6B5, AL1B1_PONAB;  Q66HF8, AL1B1_RAT;  
Q0WSF1, AL221_ARATH;  Q9SU63, AL2B4_ARATH;  Q8S528, AL2B7_ARATH;  
Q56YU0, AL2C4_ARATH;  P51648, AL3A2_HUMAN;  Q60HH8, AL3A2_MACFA;  
P47740, AL3A2_MOUSE;  Q5RF60, AL3A2_PONAB;  P30839, AL3A2_RAT;  
Q70E96, AL3F1_ARATH;  Q70DU8, AL3H1_ARATH;  Q8W033, AL3I1_ARATH;  
Q2KJC9, AL7A1_BOVIN;  Q41247, AL7A1_BRANA;  P46562, AL7A1_CAEEL;  
P83401, AL7A1_DICDI;  P49419, AL7A1_HUMAN;  Q9ZPB7, AL7A1_MALDO;  
Q9DBF1, AL7A1_MOUSE;  P25795, AL7A1_PEA;  Q64057, AL7A1_RAT;  
Q9SYG7, AL7B4_ARATH;  Q2KJH9, AL9A1_BOVIN;  P49189, AL9A1_HUMAN;  
Q9JLJ2, AL9A1_MOUSE;  Q19A30, AL9A1_ORYLA;  Q29228, AL9A1_PIG;  
Q5R8A4, AL9A1_PONAB;  Q9JLJ3, AL9A1_RAT;  Q2FF06, ALD1_STAA3;  
Q2FWD6, ALD1_STAA8;  Q2YUN1, ALD1_STAAB;  Q5HE78, ALD1_STAAC;  
Q99SD6, ALD1_STAAM;  Q7A4D8, ALD1_STAAN;  Q6GEV3, ALD1_STAAR;  
Q6G7I8, ALD1_STAAS;  Q8NVG4, ALD1_STAAW;  Q5HMA0, ALD1_STAEQ;  
Q8CNI5, ALD1_STAES;  Q4L803, ALD1_STAHJ;  Q49Z69, ALD1_STAS1;  
Q2FK94, ALDA_STAA3;  Q2G1J0, ALDA_STAA8;  Q2YV11, ALDA_STAAB;  
Q5HJK3, ALDA_STAAC;  Q99X54, ALDA_STAAM;  Q7A825, ALDA_STAAN;  
Q6GKD8, ALDA_STAAR;  Q6GCV9, ALDA_STAAS;  Q7A1Y7, ALDA_STAAW;  
Q5HLA3, ALDA_STAEQ;  Q8CN24, ALDA_STAES;  Q4L919, ALDA_STAHJ;  
P42236, ALDH1_BACSU;  Q28399, ALDH1_ELEED;  P30840, ALDH1_ENTHI;  
Q29490, ALDH1_MACPR;  P39616, ALDH2_BACSU;  P20000, ALDH2_BOVIN;  
P45959, ALDH2_GEOSE;  P12762, ALDH2_HORSE;  P05091, ALDH2_HUMAN;  
Q25417, ALDH2_LEITA;  Q29491, ALDH2_MACPR;  P81178, ALDH2_MESAU;  
P47738, ALDH2_MOUSE;  Q2XQV4, ALDH2_PIG;  Q5RF00, ALDH2_PONAB;  
P11884, ALDH2_RAT;  P47771, ALDH2_YEAST;  P46329, ALDH3_BACSU;  
P54114, ALDH3_YEAST;  O34660, ALDH4_BACSU;  O06478, ALDH5_BACSU;  
Q94688, ALDH9_POLMI;  P22281, ALDHX_YEASX;  P32872, ALDHY_YEASX;  
O74187, ALDH_AGABI;  P42041, ALDH_ALTAL;  P41751, ALDH_ASPNG;  
Q8VXQ2, ALDH_CRAPL;  P40108, ALDH_DAVTA;  Q9RYG9, ALDH_DEIRA;  
P08157, ALDH_EMENI;  Q27640, ALDH_ENCBU;  Q40255, ALDH_LINUS;  
P63938, ALDH_MYCBO;  P63937, ALDH_MYCTU;  P12693, ALDH_PSEOL;  
P33008, ALDH_PSESP;  Q9ZA11, ALDH_RHORT;  Q9RJZ6, ALDH_STRCO;  
A5F3A7, ALDH_VIBC3;  P0C6D7, ALDH_VIBCH;  P56533, BADH_GADMC;  
P46368, DHA2_CUPNH;  Q04458, HFD1_YEAST;  P46369, THCA_RHOER;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
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