ID   1.2.1.76
DE   succinate-semialdehyde dehydrogenase (acetylating).
AN   coenzyme-A-dependent succinate-semialdehyde dehydrogenase.
AN   succinyl-CoA reductase.
CA   CoA + NADP(+) + succinate semialdehyde = H(+) + NADPH + succinyl-CoA.
CC   -!- Catalyzes the NADPH-dependent reduction of succinyl-CoA to succinate
CC       semialdehyde.
CC   -!- The enzyme has been described in Clostridium kluyveri, where it
CC       participates in succinate fermentation, and in Metallosphaera sedula,
CC       where it participates in the 3-hydroxypropanoate/4-hydroxybutyrate
CC       cycle, an autotrophic CO2 fixation pathway found in some
CC       thermoacidophilic archaea.
DR   P38947, SUCD_CLOK5 ;  A4YGN0, SUCD_METS5 ;
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