ENZYME entry: EC 1.2.1.79
| Accepted Name |
|---|
| Succinate-semialdehyde dehydrogenase (NADP(+)).
|
| Reaction catalysed |
|---|
| Succinate semialdehyde + NADP(+) + H(2)O <=> succinate + NADPH |
| Comment(s) |
|---|
- This enzyme participates in the degradation of glutamate and
4-aminobutyrate.
- It is similar to EC 1.2.1.24 and EC 1.2.1.16 but is specific for
NADP(+).
- The enzyme from Escherichia coli is 20-fold more active with NADP(+)
than NAD(+).
|
| Cross-references |
|---|
| BRENDA | 1.2.1.79 |
| EC2PDB | 1.2.1.79 |
| ExplorEnz | 1.2.1.79 |
| PRIAM enzyme-specific profiles | 1.2.1.79 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.2.1.79 |
| IUBMB Enzyme Nomenclature | 1.2.1.79 |
| IntEnz | 1.2.1.79 |
| MEDLINE | Find literature relating to 1.2.1.79 |
| MetaCyc | 1.2.1.79 |
| UniProtKB/Swiss-Prot |
| A0QMB9, GABD1_MYCA1; | A1KF54, GABD1_MYCBP; | O69497, GABD1_MYCLE; |
| Q73TP5, GABD1_MYCPA; | A5TYV9, GABD1_MYCTA; | P71989, GABD1_MYCTU; |
| A0PN13, GABD1_MYCUA; | Q7TZP3, GABD2_MYCBO; | A1KJE8, GABD2_MYCBP; |
| A0R4Q0, GABD2_MYCS2; | A5U390, GABD2_MYCTA; | P96417, GABD2_MYCTU; |
| A0PST9, GABD2_MYCUA; | P94428, GABD_BACSU; | O32507, GABD_DEIRA; |
| P25526, GABD_ECOLI; | P55653, GABD_RHISN; | Q55585, GABD_SYNY3; |
|
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