ID   1.2.1.85
DE   2-hydroxymuconate-6-semialdehyde dehydrogenase.
CA   (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O + NAD(+) = (2Z,4E)-2-
CA   hydroxyhexa-2,4-dienedioate + 2 H(+) + NADH.
CC   -!- This substrate for this enzyme is formed by meta ring cleavage of
CC       catechol (EC 1.13.11.2), and is an intermediate in the bacterial
CC       degradation of several aromatic compounds.
CC   -!- Has lower activity with benzaldehyde.
CC   -!- Activity with NAD(+) is more than 10-fold higher than with NADP(+).
CC       cf. EC 1.2.1.32.
DR   P19059, DMPC_PSEUF ;  P23105, XYLG_PSEPU ;
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