ENZYME entry: EC 1.2.99.8

Accepted Name
Glyceraldehyde dehydrogenase (FAD-containing).
Alternative Name(s)
Glyceraldehyde oxidoreductase.
Reaction catalysed
D-glyceraldehyde + H(2)O + acceptor <=> D-glycerate + reduced acceptor
Cofactor(s)
FAD; Iron-sulfur; Molybdopterin guanine dinucleotide.
Comment(s)
  • The enzyme from the archaeon Sulfolobus acidocaldarius catalyzes the oxidation of D-glyceraldehyde in the nonphosphorylative Entner- Doudoroff pathway.
  • With 2,6-dichlorophenolindophenol as artificial electron acceptor, the enzyme shows a broad substrate range, but is most active with D-glyceraldehyde.
  • It is not known which acceptor is utilized in vivo.
Cross-references
BRENDA1.2.99.8
EC2PDB1.2.99.8
ExplorEnz1.2.99.8
PRIAM enzyme-specific profiles1.2.99.8
KEGG Ligand Database for Enzyme Nomenclature1.2.99.8
IUBMB Enzyme Nomenclature1.2.99.8
IntEnz1.2.99.8
MEDLINEFind literature relating to 1.2.99.8
MetaCyc1.2.99.8
UniProtKB/Swiss-Prot
Q4J6M3, CUTA_SULAC;  Q4J6M6, CUTB_SULAC;  Q4J6M5, CUTC_SULAC;  

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