ENZYME entry: EC 1.21.3.6

Accepted Name
Aureusidin synthase.
Reaction catalysed
  • 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-glucoside + O(2) <=> aureusidin 6-O-beta-glucoside + H(2)O
  • 2 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-glucoside + O(2) <=> 2 aureusidin 6-O-beta-glucoside + 2 H(2)O
  • 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-glucoside + O(2) <=> bracteatin 6-O-beta-glucoside + H(2)O
Cofactor(s)
Copper.
Comment(s)
  • Plays a key role in the yellow coloration of flowers such as Antirrhinum majus (snapdragon).
  • The enzyme is a homolog of plant polyphenol oxidase and catalyzes two separate chemical transformations, i.e. 3-hydroxylation and oxidative cyclization (2',-dehydrogenation).
  • H(2)O(2) activates reaction (1) but inhibits reaction (2).
  • Originally considered to act on the phenol but now thought to mainly act on the 4'-O-beta-glucoside in vivo.
Cross-references
BRENDA1.21.3.6
EC2PDB1.21.3.6
ExplorEnz1.21.3.6
PRIAM enzyme-specific profiles1.21.3.6
KEGG Ligand Database for Enzyme Nomenclature1.21.3.6
IUBMB Enzyme Nomenclature1.21.3.6
IntEnz1.21.3.6
MEDLINEFind literature relating to 1.21.3.6
MetaCyc1.21.3.6
UniProtKB/Swiss-Prot
Q9FRX6, AS1_ANTMA

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